Jonathan Reid, returning to London from the Great War in 1918, awakes in a mass grave as a vampire. Overwhelmed with bloodlust, he causes the death of his sister Mary, who was searching for his body nearby. Reid takes shelter from vampire hunters in an abandoned house and starts hearing the disembodied voice of his maker, a typical feature in the progeny of vampires. Realising London is profuse with corpses, he follows a blood trail to a bar. The bartender points Reid to William Bishop, a suspicious patron. Bishop is caught feeding on a man named Sean Hampton and is killed by the vampire Lady Ashbury. Doctor Edgar Swansea rescues Hampton and hires Reid to practice medicine at Pembroke Hospital.